10 Best Eye Drops Gel For Dry Eyes of 2025

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Refresh Liquigel Lubricant Eye Gel, 2 Bottles 0.5 Fl Oz (15mL) Each Sterile (30mL)

Why We Love It

Long-lasting relief for dry eyes day or night
Soothing gel formula
Safe to use with contact lenses
No shaking required prior to use, unlike Systane Gel Drops
Value size - two convenient multi-dose bottle
Safe to use as often as needed
Inventiv Health Research and Insights Treatment Answers, MAT ending October 2016

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Why We Love It

Long-lasting relief for dry eyes day or night
Soothing gel formula
Safe to use with contact lenses
No shaking required prior to use, unlike Systane Gel Drops
Value size - two convenient multi-dose bottle
Safe to use as often as needed
Inventiv Health Research and Insights Treatment Answers, MAT ending October 2016

9.5

Excellent

iVIZIA

iVIZIA Lubricant Eye Gel for Severe and Nighttime Dry Eye Relief, Preservative-Free, Moisturizing, 30 Sterile Single-Use Vials Packaging May Vary

8% Off

Main Highlights

Your Dry Eyes Deserve Better: Thicker formula for overnight use, our gel provides more lubrication and moisture than our daytime formula and is ideal to relieve severe dry eye symptoms.
Free of Irritating Preservatives: Sterile, preservative-free, and can be used before or after eye surgery.
Sterile Single-Use Vials: iVIZIA Lubricant Eye Gel is offered in preservative-free sterile, single-use vials that are convenient and easy to use for severe dry eye or nighttime use.
IVIZIA We See a Better Way: for healthy, comfortable eyelids

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Main Highlights

Your Dry Eyes Deserve Better: Thicker formula for overnight use, our gel provides more lubrication and moisture than our daytime formula and is ideal to relieve severe dry eye symptoms.
Free of Irritating Preservatives: Sterile, preservative-free, and can be used before or after eye surgery.
Sterile Single-Use Vials: iVIZIA Lubricant Eye Gel is offered in preservative-free sterile, single-use vials that are convenient and easy to use for severe dry eye or nighttime use.
IVIZIA We See a Better Way: for healthy, comfortable eyelids

9.5

Excellent

Refresh

Refresh Optive Gel Drops Lubricant Eye Gel For Dry Eyes, 0.33 Oz Sterile

20% Off

Main Highlights

Extended relief plus protection for dry, irritated eyes
Our most comprehensive gel formula
Anytime relief, day or night
Feels like a drop but works like a gel for lasting comfort
Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
#1 doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

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Main Highlights

Extended relief plus protection for dry, irritated eyes
Our most comprehensive gel formula
Anytime relief, day or night
Feels like a drop but works like a gel for lasting comfort
Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
#1 doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

Best Value

9.2

Excellent

Refresh

Refresh Celluvisc Lubricant Eye Gel For Dry Eyes, Preservative-Free Drops, 0.01 Fl Oz Single-Use Containers, 30 Count

36% Off

Main Highlights

Original strength gel formula
Relieves dry, burning, irritated eyes
Alleviates discomfort
Keeps eyes feeling better longer
#1 doctor recommended with over 30 years of experience.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey

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Main Highlights

Original strength gel formula
Relieves dry, burning, irritated eyes
Alleviates discomfort
Keeps eyes feeling better longer
#1 doctor recommended with over 30 years of experience.* *REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey

9.0

Excellent

Systane

Systane Nighttime Lubricant Eye Ointment 3.5g Tube

Main Highlights

#1 Dr Recommended Brand of Artificial Tears*
Provides nighttime relief of dry eye symptoms
Ointment soothes and protects against dry, irritated eyes
Forms long-lasting, protective layer on eyes while you sleep
Safe, preservative-free formula

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Main Highlights

#1 Dr Recommended Brand of Artificial Tears*
Provides nighttime relief of dry eye symptoms
Ointment soothes and protects against dry, irritated eyes
Forms long-lasting, protective layer on eyes while you sleep
Safe, preservative-free formula

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8.8

Very Good

Refresh

Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile

11% Off

Main Highlights

Original strength gel formula
Relieves dry, burning, irritated eyes
Alleviates discomfort
Keeps eyes feeling better longer
Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

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Main Highlights

Original strength gel formula
Relieves dry, burning, irritated eyes
Alleviates discomfort
Keeps eyes feeling better longer
Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun

8.6

Very Good

Systane

Systane Lubricant Eye Gel Drops, 10-mL (Packaging May Vary)

17% Off

Main Highlights

#1 Dr Recommended Brand of Artificial Tears*
Thicker eye drop formulation that creates a protective shield over your eyes.
Convenience of a drop with a protection of a gel.
For the temporary relief of burning and irritation due to dryness of the eye
NOTE: PRODUCT PACKAGING MAY VARY

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Main Highlights

#1 Dr Recommended Brand of Artificial Tears*
Thicker eye drop formulation that creates a protective shield over your eyes.
Convenience of a drop with a protection of a gel.
For the temporary relief of burning and irritation due to dryness of the eye
NOTE: PRODUCT PACKAGING MAY VARY

8.3

Very Good

TheraTears

TheraTears Liquid Gel Nighttime Lubricating Eye Drops for Dry Eyes, Single-Use Vials, 30 Count

5% Off

Main Highlights

Dry eye relief without preservatives: TheraTears nighttime lubricating eye drops in single-use vials provide soothing overnight relief from dry eye symptoms, 4x the active lubricating ingredient of TheraTears original, no preservatives for sensitive eyes
Instant hydration: TheraTears eye drops restore eyes natural balance and deliver hydration relief for dry eyes, because hydration is essential for eye health
Electrolytes: TheraTears eye drops unique formula contains OxyLytes, the 5 vital electrolytes found in natural tears
Created by an ophthalmologist: The TheraTears formula was created by an ophthalmologist, following 18 years of research, for a one-of-a-kind eye drop
Doctor-recommended: TheraTears is a doctor-recommended brand (per ProVoice Survey data collected 9/1/23-8/31/24), created to bring balance and hydration to dry eyes; your purchase may be FSA/HSA eligible, check your health plan for details

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Main Highlights

Dry eye relief without preservatives: TheraTears nighttime lubricating eye drops in single-use vials provide soothing overnight relief from dry eye symptoms, 4x the active lubricating ingredient of TheraTears original, no preservatives for sensitive eyes
Instant hydration: TheraTears eye drops restore eyes natural balance and deliver hydration relief for dry eyes, because hydration is essential for eye health
Electrolytes: TheraTears eye drops unique formula contains OxyLytes, the 5 vital electrolytes found in natural tears
Created by an ophthalmologist: The TheraTears formula was created by an ophthalmologist, following 18 years of research, for a one-of-a-kind eye drop
Doctor-recommended: TheraTears is a doctor-recommended brand (per ProVoice Survey data collected 9/1/23-8/31/24), created to bring balance and hydration to dry eyes; your purchase may be FSA/HSA eligible, check your health plan for details

8.1

Very Good

Genteal

Genteal Tears Gel Drops, 8 ml

19% Off

Main Highlights

Product Type:Medication
Item Package Dimension:1.75 " L X1.25 " W X3.88 " H X
Item Package Quantity:1
Country Of Origin: United States

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Main Highlights

Product Type:Medication
Item Package Dimension:1.75 " L X1.25 " W X3.88 " H X
Item Package Quantity:1
Country Of Origin: United States

8.1

Very Good

BLINK

BLINK GelTears Eye Drops for Dry Eyes, Gel Lubricating Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

31% Off

Main Highlights

Relief with Every Blink: Experience immediate and long-lasting dry eye symptom relief with Blink GelTears eye drops for dry eyes. This thicker, more viscous lubricating formula is for enhanced comfort and great for daytime and nighttime use
Hydration Boost with Hyaluronate: Our gel lubricating eye drops for dry eyes instantly soothe and comfort. It contains our highest level of hyaluronate to provide longer lasting relief for moderate to severe dry eye symptoms
Day & Night Relief: Blink eye drops are formulated for daytime and nighttime use and provides superior end-of-day comfort (in an Ocular Lubricant questionnaire, comfort ratings were statistically significantly higher for Blink Geltears vs. Allergan's Refresh Optive Liquid Gel after 7 days and 30 days). These lubricant eye drops maximize hydration for enhanced comfort, in addition to instantly soothing & comforting
Reduce Everyday Discomfort: These drops are an extra moisturizing gel for enhanced comfort. Work with every blink to restore your tears' natural balance and maximize hydration
Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated. Blink products provide comfort and hydration, to help your eyes feel moisturized & protected

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Main Highlights

Relief with Every Blink: Experience immediate and long-lasting dry eye symptom relief with Blink GelTears eye drops for dry eyes. This thicker, more viscous lubricating formula is for enhanced comfort and great for daytime and nighttime use
Hydration Boost with Hyaluronate: Our gel lubricating eye drops for dry eyes instantly soothe and comfort. It contains our highest level of hyaluronate to provide longer lasting relief for moderate to severe dry eye symptoms
Day & Night Relief: Blink eye drops are formulated for daytime and nighttime use and provides superior end-of-day comfort (in an Ocular Lubricant questionnaire, comfort ratings were statistically significantly higher for Blink Geltears vs. Allergan's Refresh Optive Liquid Gel after 7 days and 30 days). These lubricant eye drops maximize hydration for enhanced comfort, in addition to instantly soothing & comforting
Reduce Everyday Discomfort: These drops are an extra moisturizing gel for enhanced comfort. Work with every blink to restore your tears' natural balance and maximize hydration
Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated. Blink products provide comfort and hydration, to help your eyes feel moisturized & protected

Discounted Eye Drops Gel For Dry Eyes

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

34% OffFree Shipping

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary

31% Off

BLINK GelTears Eye Drops for Dry Eyes, Gel Lubricating Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

The information below is per-pack only

TheraTears Extra Dry Eye Drops, Twin Pack, 2 Bottles x 0.5 fl oz (Pack of 1)

28% OffFree Shipping

TheraTears Extra Dry Eye Drops, Twin Pack, 2 Bottles x 0.5 fl oz (Pack of 1)

Immediate dry eye relief: TheraTears EXTRA Dry Eye Therapy lubricating eye drops provide immediate relief from dry eye symptoms; this formula delivers EXTRAordinary relief with up to 12 hours of hydrating comfort

Systane Lubricant Eye Gel, Nighttime, 0.35-Ounces (package may vary)

27% OffFree Shipping

Systane Lubricant Eye Gel, Nighttime, 0.35-Ounces (package may vary)

Dr Recommended Brand of Artificial Tears

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

24% OffFree Shipping

Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers

FAST-ACTING: Rapid relief to comfort dry, irritated eyes

BLINK Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

20% OffFree Shipping

BLINK Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

Relief with every Blink: Experience extended dry eye symptom relief with Blink Triple Care Lubricating Eye Drops. This 3-in-1 formula instantly soothes, gives extra long-lasting hydration, and seals in moisture.

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

16% OffFree Shipping

Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)

Dr Recommended Brand of Artificial Tears

GenTeal Tears Lubricant Eye Drops, Moderate Liquid Drops, Twin Pack ,0.5 Fl Oz (Pack of 2) Package May Vary

11% OffFree Shipping

GenTeal Tears Lubricant Eye Drops, Moderate Liquid Drops, Twin Pack ,0.5 Fl Oz (Pack of 2) Package May Vary

Moderate Dry Eye Symptom Relief

TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Vials, 30 Count (Pack of 2)

TheraTears Liquid Gel Nighttime Eye Drops for Dry Eyes, 30 Vials, 30 Count (Pack of 2)

Dry eye relief without preservatives: TheraTears nighttime lubricating eye drops in single-use vials provide soothing overnight relief from dry eye symptoms which may be better for people with sensitive eyes, with 4x the active lubricating ingredient of TheraTears original, no preservatives for sensitive eyes